DAILY SCIENCE FIX - SWINE FLU - Born in the USA?
Did the swine flu originate in the USA...?
At the risk of doing a post on something I barely understand, the swine flu or H1N1 does appear to have genetic roots in the good 'ole US. Wired has the expose:
As Wired.com reported on Tuesday, geneticists studying the composition of viruses taken from swine flu victims described it as the product of a DNA swap between North American and Eurasian swine flu strains.
On Wednesday, Columbia University biomedical informaticist Raul Rabadan added new information on the virus' family history in a posting to ProMed, a public health mailing list. His description paralleled that of other researchers who had analyzed the new strains, but with an extra bit of detail. Six of the genes in swine flu looked to be descended from "H1N2 and H3N2 swine viruses isolated since 1998."
H3N2 -- the letters denote specific gene variants that code for replication-enhancing enzymes -- is the name of a hybrid first identified in North Carolina in 1998, the tail end of a decade which saw the state's hog production rise from two million to 10 million, even as the number of farms dropped. H3N2 originated in a relatively benign swine flu strain first identified in 1918, but had absorbed new genes from bird and human flus.
At the genetic level, the years that followed remain a mystery -- hog flus are poorly monitored, compared to human influenza. But eventually an H3N2 spawn merged with a strain of Eurasian pig flu, producing the swine flu variant that's now infecting humans.
Experts contacted by Wired.com agreed with Rabadan's analysis. For researchers who track the evolution of influenza viruses, the news was chilling.
The point here is that industiral pig farmers in America (and no doubt elsewhere) raise pigs in very unnatural and unhealty ways.
Industrial farms are super-incubators for viruses," said Bob Martin, former executive director of the Pew Commission on Industrial Animal Farm Production, and a long-time critic of the so-called "contained animal feeding operations."
At an environmental level, the conditions which shaped H3N2 and H1N2 evolution, and increased the variants' chances of taking a human-contagious form, are well understood. High-density animal production facilities came to dominate the U.S. pork industry during the late 20th century, and have been adopted around the world. Inside them, pigs are packed so tightly that they cannot turn, and literally stand in their own waste.
Diseases travel rapidly through such immunologically stressed populations, and travel with the animals as they are shuttled throughout the United States between birth and slaughter. That provides ample opportunity for strains to mingle and recombine. An ever-escalating array of industry-developed vaccines confer short-term protection, but at the expense of provoking flu to evolve in unpredictable ways.
As much as I am a consumer of mass produced meat, the more I know about large industrial food production, the more I want to grow and raise all I eat.
In any event, if we want to prevent the next pandemic, we dont have to look to foreign shores to find changes that need to be made.
In other words we reap what we sow.
Stay Tuned...
















The first thing that came to mind when I heard of these reports.
It was the Darn Yankees. The neighbor to the North, they were the culprits of the collapse of the Mexican tourist industry.
No need to shut down the borders, see as how your the disease spreaders. Maybe if you pay us we will come to your country. Si Senor
My second thought after reading your post. We deinitely reap what we sow. What to do now? I love bacon and eggs. Canadian cut Bacon.
What if it really started with the Canadians?
Yeah lets blame them?
May 3, 2009 7:18 AM | Reply | Permalink
I was reading how hog farmers are concerned that their pigs will get the swine flu from humans and hurt production. This particular new strain of H1N1 has only been found in humans, so far.
http://www.timesofmalta.com/articles/view/20090501/world-news/who-changes-name-of-flu-virus-strain
Oops, too late. Canadian pigs haz flu now.
http://www.timesofmalta.com/articles/view/20090503/world-news/h1n1-flu-found-in-canadian-pig-herd
Oh, and....if you think mass produced pigs have it bad, you don't even wanna know about mass poultry production.
May 3, 2009 11:00 AM | Reply | Permalink
If people had any idea of how compromised our food distribution system is in this country, we'd be a nation of anorexics.
Salmonella is a good example - it's in the fields, it's transferred to the harvesting machines, it's on the conveyer belts, it's in the water lines used to wash the spinach, it's in the containers used to package the spinach, it's then in the trucks used to ship the product, it is on the produce counters, the belt in the checkout line and then it ends up in your refrigerator. Every single person and surface it has touched from the beginning to the end is possibly infected and a potential carrier that spawns a new outbreak somewhere else.
Those gorgeous fruit and vegetable displays that grocers love to arrange on their produce shelves and constantly spray to keep the produce looking delicious - that spray drips down on other produce, it's shaken on other products, it's on your hands when you pick it up, it's in the grocery carts and then on to the checkout belts.
The simple answer is to disinfect and clean surfaces that have come in contact with the infected product, but no one, at any time along the system is going to do this because it costs them money and the FDA will not enforce the regulations and laws governing food safety in this country.
May 3, 2009 12:42 PM | Reply | Permalink
While I dont disagree with your premise, Im not sure I agree with your solution. I think that too much cleaning and disinfecting of things are also problematic. And while I dont have time right now, I suspect our relationship with salmonella is complex. Im always surprised by reports that show salmonella and staph are on all the surfaces we come into contact with regularly and yet outbreaks are infrequent. More must be going on.
See my previous posts on H. Pylori and The Auto Immune System
May 3, 2009 3:45 PM | Reply | Permalink
Well, nothing is going to stop it (salmonella), and it is not necessarily in the best interest of evolution to stop it, afterall, DNA is bacterial in nature, but we do need to control it, just as we need to control staph, especially in hospitals - it is dangerous to those with weak or weaker immune systems. If hospital staff would just wash their hands more often (and better) we could eliminate many hospital deaths. One reason why I find this latest outbreak of swine flu interesting is because the illness and consequential deaths seem to be concentrated in certain demographics and those demographics seem not to have immunity to it.
Viruses are the most fascinating life forms on this planet. We can see evolution working in real time.
May 3, 2009 5:54 PM | Reply | Permalink